
This derm favorite is the only prescription-strength retinoid (adapalene) available OTC, and it treats everything from acne to discolorations to wrinkles. Apply a gentle moisturizer on top since it acts like more of a treatment. If you experience irritation, apply your moisturizer underneath to provide a bit of a barrier.
One reviewer over 60 said that, with some patience, her skin eventually cleared up after a few months of using the product. “I am now flabbergasted! My skin hardly breaks out now!” she wrote. “I have had acne for as long as I can remember. Thanks to this fabulous product, I have much better skin now. Hardly any acne! It seems to have purged my skin to a clearer state.”

“With this cream, you don’t need to worry about whether or not it’s only going to help with puffiness or just improve crow’s feet because it really does do it all,” says Joel Schlessinger, M.D., board-certified dermatologist and cosmetic surgeon. Its formula utilizes powerful growth factors to smooth and firm the eye area, while caffeine improves the appearance of puffiness and dark circles.
“This is by far the best eye cream I’ve tried, and I’ve tried quite a few,” said a 51-year-old reviewer who has been using the products for two years.